It was originally developed as part of research into isolating specific regions of the growth hormone molecule associated with particular activity, separate from the full-length hormone's broader receptor-binding profile
AES were transformed by electroporation in M
Each freeze-thaw cycle creates ice crystals that can physically disrupt peptide structure, and the process concentrates the peptide at the boundary between frozen and unfrozen regions, potentially causing aggregation
In experimental models of inflammatory bowel disease and intestinal injury, the peptide consistently improves mucosal integrity, reduces local and systemic inflammatory mediators, and counters damage induced by stressors such as NSAIDs, alcohol, and other toxic agents
It is naturally present in animal-based foods and can also be found in fortified products and dietary supplements