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It was finally approved by NICE for treating severe persistent allergic asthma last year, after previously being rejected in draft guidance because of question marks over its cost-effectiveness

This dual-incretin therapy has been studied for its effects on appetite centers in the brain, helping patients maintain better control over cravings and eating patterns

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The demonstration that depletion of ataxin 2 ameliorates TDP-43 proteinopathy has led to genetic therapy approaches in preclinical models and a clinical trial