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GLP-1 agonists work by mimicking the effects of this hormone, resulting in several beneficial metabolic actions: Stimulate insulin secretion from the pancreas in response to meals Suppress appetite by acting on appetite centers in the brain Slow gastric emptying , which helps prolong satiety after eating Reduce glucagon secretion , helping to lower blood sugar levels Together, these effects make GLP-1 agonists an effective tool not only for diabetes management but also for sustainable, medically supervised weight loss