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40 When tirzepatide was compared with dulaglutide in people with type 2 diabetes and atherosclerotic cardiovascular disease, tirzepatide was noninferior to dulaglutide in reducing time to a composite of death from cardiovascular causes, myocardial infarction or stroke

Mice homozygous for a dominant negative Pax6 mutation (SEYNeu) have repressed Gcg expression in enteroendocrine cells in the small and large bowel and absence of immunoreactive GLP-1 and GLP-2 [109]

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