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Transition metalbased carriers (e.g., MnO, Cu 2 , Fe 3 ) provide an additional layer of functionality, as they can both deplete intracellular GSH and generate reactive oxygen species, thereby amplifying oxidative stress within tumors

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Riboflavin, niacin amide, selenium, lipoic acid and glutathione reductase are all essential co-factors for generating reduced glutathione

[1] Niacinamide in high doses can sometimes cause nausea, heartburn, or a sensation of warmth

Roles of dextrans on improving lymphatic drainage for liposomal drug delivery system