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Over a median follow up of 3.6 years, there was a 50% reduction in progression to dementia (placebo vs GLP-1 receptor agonist: 15 vs 32 patients)

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Multiple studies suggest that GLP-1RAs demonstrate significant anti-inflammatory properties across various cell and tissue types, effectively suppressing sustained inflammatory responses during chronic inflammation [94]

Retatrutide has been tested in both Phase 2 and Phase 3 clinical trials involving hundreds of participants across multiple dose groups

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