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Whether you take semaglutide or tirzepatide , the mechanism of appetite suppression, calorie reduction, and potential muscle loss is similar

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In the same trial, tirzepatide and semaglutide were compared once weekly in the open-label, phase III SURPASS-2 experiment

The hazard ratios (HRs) and confidence intervals (CIs) were calculated using a stratified Cox proportional hazards model in which treatment was considered a fixed effect and trial-level cardiovascular risk as the stratification factor