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Over-the-counter remedies that may help If lifestyle changes aren't enough, there are safe over-the-counter options to consider: Osmotic laxatives like polyethylene glycol (Miralax) draw water into the bowel to soften stool Magnesium citrate works similarly and is often recommended by experts for GLP-1-related constipation Stool softeners like docusate sodium can make stools easier to pass without stimulating the intestines Fiber supplements can help, but start with a low dose and increase gradually while drinking plenty of water Talk to your doctor or dietitian before trying any supplements
Designed for studies into incretin mimetics and multi-receptor agonists
In addition, the compound decreases sodium resorption in the proximal nephron and stimulates renin release, resulting in angiotensin-dependent contraction of the draining arterioles [31,32]
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