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They are bioactive molecules with characterized mechanisms of action, published clinical data, and, in many cases, FDA approval

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It also upregulates nerve growth factor (NGF) in enteric neurons, promoting vagal nerve repair the vagus controls 80% of parasympathetic input to the stomach and is commonly damaged in diabetic and idiopathic gastroparesis

StrataGene identifies, I think, two or three commonly found genetic variants in DAO