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Regarding IL10 expression, measured using immunofluorescence analysis, the treatment with LArginine significantly increased IL10 levels on day 4 (in both the pancreatic acinar cells and islets) and day 8 (in the acinar cells) compared to the Control group
The ENS regulates gut motility, secretion, and blood flow and communicates bidirectionally with the central autonomic circuits via the vagus nerve and sympathetic pathways [20]
To avoid non-specific cytotoxicity, especially in human cells, we additionally required low toxicity in U2-OS human bone osteosarcoma cells that we and others use routinely for image analysis due to their flattened morphology (Supplementary Fig
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