Long-term data shows sustained results over 68+ weeks when the medication is continued consistently
1H NMR (DMSO- d6, D20, 300 MHz): 8.6 (s, 1H), 8.15 (s, 1H), 7.85 (bd, 1H), 7.55 (d, 2H), 6.95 (d, 2H), 6.6 (m, 4H), 6.2 (d, 1H), 5.68 (d, 1H), 5.2 (d, 1H), 4.6 (t, 1H), 4.5 (m, 3H), 4.5-4.0 (m, 11H), 3.2-2.8 (m, 6H), 2.8-2.5 (m, 8H), 2.4 (m, 5H), 2.2-2.0 (m, 14H), 2.0-1.7 (m, 7H), 1.6-1.3 (m, 13H), 1.25 (d, 8H), 1.1-0.95 (dd, 8H), 0.75 (m, 10H), 0.6 (d, 2H)
Most people experience no adjustment phase at all
Seek medical evaluation if symptoms are rapidly worsening, affecting balance or walking, involving weakness, or not improving after several weeks of supplementation
Headache days improved numerically more with exenatide than placebo, but the trial was small and not definitive for headache outcomes