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Escalating dose increases side effect risk without proportional benefit

Mol Cell 15: 767776 Hwang C, Sinskey AJ, Lodish HF (1992) Oxidized redox state of glutathione in the endoplasmic reticulum

Liebmann J, Fisher J, Lipschultz C et al (1995) Enhanced glutathione peroxidase expression protects cells from hydroperoxides but not from radiation or doxorubicin

In normoxic tumor zones, cancer cells can utilize oxidative metabolism more efficiently by scavenging CAF-derived metabolites, thereby conserving their own glucose and glutamine pools (148)

Regular evaluations track physical recovery, energy levels, pain reduction and functional improvement throughout the peptide therapy program