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Ipilimumab was the first CTLA-4-blocking antibody approved by the US FDA for the treatment of human cancers

10 However, SCORE2-Diabetes lacks a specific categorisation for individual countries in Asia, raising questions about its applicability as a reference for patients in these countries, including Thailand

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M1 macrophage-derived exosomes were transfected with NF-B p50 siRNA and miR-511-3p to foster M1 polarization and subjected to surface modification with the IL4R-targeting IL4RPep-1 peptide (CRKRLDRNC) using a phospholipid anchor