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Side effects can also occur, such as: Abdominal pain Nausea Vomiting Diarrhea Gastroparesis (delayed stomach emptying) Pancreatitis Possible increased risk of sudden blindness Cost and insurance coverage Health insurance coverage varies widely for GLP-1 medications and can cost a patient hundreds of dollars per month

On April 30, 2026, the FDA proposed to exclude semaglutide, tirzepatide, and liraglutide from the 503B bulks list, citing no clinical need for large-scale compounding of these drugs

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