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Together, these findings indicate that GSH catabolism by GGTs is an important source of amino acids, including cysteine

Despite their indispensability, amino acids are often scarce in the tumour microenvironment 4 , which drives tumours to develop strategies to import and synthesize them 5,6,7

According to the definition: antioxidants are compounds that, when present in low concentration compared to an oxidized substrate, can inhibit the processes of that substrate oxidation, scavenge or detoxify the already formed ROS, and repair ROS-induced damage of a target molecule (Waddington et al., 2008)

Native GSH maintains a half-life of 2-3 hours in plasma for both IV and oral forms