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Research suggests DSIP modulates GABAergic and glutamatergic neurotransmission, interacts with the hypothalamic-pituitary-adrenal (HPA) axis to reduce cortisol and ACTH levels, and may influence circadian rhythm regulation through effects on melatonin and serotonin pathways

Oral B12 (given sublingually) MB12 liquid The research used 500 mcg per day Although B12 is a very safe vitamin, always be on the lookout for these symptoms when using high doses: Headache Nausea and vomiting Diarrhea Fatigue or weakness Tingling sensation in hands and feet Possible explanations for elevated B12 (without supplementation) in the blood SIBO (Small Intestine Bacterial Overgrowth) SIBO may cause very elevated levels of B12 in the blood

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The differential diagnosis is broad, from diabetes to B12 deficiency to autoimmune conditions to malignancy, and treatment varies dramatically by cause

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