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Bacterial growth likely if any contamination occurred during reconstitution or drawing doses

By constructing humanized animal models to modify the host, such as transplanting human hematopoietic stem cells or human liver cells into immunodeficient mice to carry functional human immune cells or target organs, the interaction between engineered bacteria and human cells can be evaluated in a living environment

If breakouts persist beyond six weeks with no improvement, you're not experiencing purging

Epub 2005 Mar 29