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Muscle endurance: It buffers lactic acid, which delays muscle fatigue during strenuous exercise

The starting dose for severe deficiency is typically 1500mcg (the full dose of the 1ml vial) given daily or on alternate days for 1 to 2 weeks, or until haematological remission is achieved

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This effect attenuates postprandial glucose excursions, though tachyphylaxis (reduced response over time) to this particular effect may occur with chronic GLP-1 receptor agonist therapy

When combined, these peptides create complementary effects: semaglutide creates a caloric deficit and stabilizes blood glucose, while sermorelin supports lean muscle retention and metabolic acceleration