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This state of oxidative stress is a fundamental reason why many of the chronic diseases that shorten our lifespan take hold

[DOI] [PMC free article] [PubMed] [Google Scholar] 134.Tepes M., Gojkovic S., Krezic I., Zizek H., Vranes H., Madzar Z., Santak G., Batelja L., Milavic M., Sikiric S., et al

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350,351 In addition to mediating the adaptive and innate immune responses, MHCI molecules contribute to controlling axonal and synaptic growth and participate in the regulation of synaptic plasticity and synaptic homeostasis in the presynaptic and postsynaptic regions associated with glutamate