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Nature Communications, Apr 10, 2025
7.6% among those in the third decade
The most common side effects are digestive: - Nausea (usually improves over time) - Vomiting - Diarrhea or constipation - Stomach pain These are usually manageable with slow dose increases
A more comprehensive understanding of the relationship between lactylation and other PTMs, as well as the regulatory strategies for protein lactylation, will aid in developing new therapeutic ideas and expanding the treatment potential of lactylation modifications in CNS diseases
Patients often choose it for sharper focus, improved vitality, and graceful aging
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