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GSH brain concentrations are not commonly measured using 1 H-MRS, because relative to other 1 H-MRS-detectable neurochemicals (e.g., creatine (Cr), choline, N -acetylasparate), GSH concentrations are substantially lower
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However, it is a cold extraction method that yields lower amounts of secondary metabolites compared to hot extraction techniques due to slower diffusion rates (Saptarini & Wardati, 2020)
