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[ref] Feedback loop: High levels of homocysteine increase inflammatory cytokines

Overproduction of l-cysteine and l-cystine by expression of genes for feedback inhibition-insensitive serine acetyltransferase from Arabidopsis thaliana in Escherichia coli

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Therefore, therapies that can restore the wild-type activities from p53 mutants have the potential to cause p53-mediated tumor suppressive effects