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[DOI] [PMC free article] [PubMed] [Google Scholar] 77.Durham W.J., Casperson S.L., Dillon E.L., Keske M.A., Paddon-Jones D., Sanford A.P., Hickner R.C., Grady J.J., Sheffield-Moore M

Azoles inhibit the activity of 14--demethylase (CYP51) by binding to the heme group in its active site, thus blocking the synthesis of ergosterol, a key component of the fungal cell membrane, and exerting an antifungal effect [47]

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