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Systemic effects of GLP-1 RAs, mediated via GLP-1 receptors in other organs and systems, include enhanced endothelial function and myocardial metabolism, natriuresis and anti-inflammatory and blood pressure-lowering effects
Gibney MA, Arce CH, Byron KJ, Hirsch LJ
This was notably not due to any new safety concerns and may potentially be driven by the manufacturers reluctance to introduce a black triangle to ensure clinician and patient awareness of the increased monitoring requirements in type 1 diabetes [29]
Additionally, GHK-Cu promotes the synthesis of glycosaminoglycans, complex molecules that enhance hydration, elasticity, and skin firmness