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For example, a kainite-model of TLE showed that seizures increased the steady-state mitochondrial ROS levels in the forebrain, which caused deficits in mitochondrial respiration, exemplified by the significant reduction of oxygen consumption by hippocampal neurons ( Discussion The complex and elaborate nature of cortical development, during which a large amount of ATP is produced and utilized, necessitates a deeper understanding of metabolized macromolecules and the mitochondria

Katinka van de Ven is a Research Fellow at the National Drug and Alcohol Research Centre, UNSW and Renee Zahnow is a Postdoctoral Research Fellow in the Faculty of Humanities and Social Sciences, The University of Queensland This article was originally published on The Conversation

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It is not approved by the FDA or any regulatory authority for human use, and safety and efficacy in humans have not been established outside of any structured clinical trials referenced

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