In contrast, low stiffness increases the activity of the Ras-related GTPase RAP2 which inactivates RhoA and induces the phosphorylation of the large tumor suppressor kinase 1/2 (LATS1/2)
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Compared to controls, SLC25A39-deficient A549 and H1299 cells exhibited significantly elevated reactive oxygen species (ROS) levels, as indicated by increased green fluorescence intensity of DCF-DA staining (Fig
