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Topiramate is often started at a low dose and gradually increased to minimize side effects

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the exact percentages, and the claim that the product becomes unsafe past the window, are unsupported

It is important to note that lipoedema requires a multidisciplinary approach, and any medication should be considered only as part of a comprehensive management plan

Beyond Weight Loss: Metabolic Improvements Participants also saw improvements in cardiometabolic health markers: Blood pressure: Systolic BP decreased by 7.4 mmHg Triglycerides: Fell by 30% HDL cholesterol: Increased by 8% (the "good" cholesterol) Liver fat: Reduced by 50% based on imaging studies HbA1c: Decreased by 0.4% even in participants without diabetes Visceral fat: Reduced by 42% (more than total weight loss percentage) Some of these improvements (particularly the visceral and liver fat reductions) are larger than the overall weight loss, which points to direct metabolic effects from the glucagon receptor activation