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1 Safety The most common adverse effect of semaglutide is an increase in heart rate, with an increase of 10 to 19 beats per minute in 41% of patients (34% with placebo) and 20 beats per minute in 26% of patients (vs

What this means for real people For readers wondering whether the science or the price should sway decisions, here is a practical take by experts - If your goal is diabetes control and modest weight loss, semaglutide formulations (Ozempic) remain a mainstream choice, supported by cardiovascular outcomes data and diabetes approvals

"The biggest thing I've seen in my practice is that patients who are obese can take these medications and have dramatic reductions in their weight, while doing it in a healthy fashion with a tolerable treatment," Dr

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Tran A, Retnakaran R, Zinman B, Kramer CK