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Many new questions about the mechanism of DNA methylation-mediated gene expression regulation in mammals have appeared: (i) what is the role of non-CG methylation in stem cells, in which it appears enriched on transcribed strands of gene bodies of highly active genes (Lister et al., 2009), and does it occur in different cell types as suggested in some studies

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Moreover, phospho-BCL-XL (Ser62) stabilizes G2 arrest by binding to and co-localizing with Cdk1 (cdc2) in nucleolar structures to avoid rapid nucleolar disassembly associated with mitosis onset, playing an unexpected role in the G2 phase checkpoint downstream of DNA damage distinct from its anti-apoptotic function 22