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KryukovGVCastellanoSNovoselovSVLobanovAVZehtabOGuigRet alCharacterization of mammalian selenoproteomes
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PA-treated cells exhibited an increased mitochondrial ROS production, which was abrogated by fer-1, validating the important role of mitochondrial ROS in PA-induced ferroptosis only for SUM-159 cells (Figs
2 Data suggest that plasma and hepatic GSH also are decreased in patients with acute viral hepatitis, or chronic liver injury from a variety of causes such as chronic hepatitis, nonalcoholic liver cirrhosis, and alcoholic liver disease
Additionally, we demonstrated that HIF-1 acts upstream of receptor-mediated mitophagy, based on our findings that loss of HIF-1 functionachieved through either pharmacological inhibition (PX-478) or genetic downregulationmarkedly suppressed BNIP3/NIX-mediated mitophagy
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