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In the brain, IRAP cleaves both vasoactive peptides and neuropeptides

It is becoming more widely acknowledged that ferroptosis, a newly identified kind of controlled cell death triggered by iron-dependent lipid peroxidation, plays a major role in the pathophysiology of ARDS ( Figure 2 )

Throughout this review, mechanistic insights derived from cellular and animal models are discussed separately from translational observations and human clinical or observational data

What is changing, and why Oestrogen is one of the body's most powerful anti-inflammatory hormones

Numerous studies have highlighted the impact of oxidative stress on MSC differentiation into osteocytes [40] and chondrocytes [41] via the regulation of differentiation signaling cascades [42, 43]