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Isoflurane inhibits synaptic vesicle exocytosis through reduced Ca 2+ influx, not Ca 2+ exocytosis coupling
The ensuing pathology, largely consisting of macrophage and lymphocyte infiltration of mainly the spinal cord, recapitulates the inflammatory pathology of acute MS lesions in a number of respects, but differs from MS in important ways: many EAE variants exhibit only limited demyelination confined to the spinal cord white matter, contrasting with extensive brain pathology also prominently affecting cortical gray matter in MS
doi: 10.1186/s12943-024-01999-9 102
Common stacks include Ipamorelin, CJC-1295, or BPC-157
This means the body can put glutathione to work right away, maximizing its detoxifying potential
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