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doi: 10.3389/fpls.2018.00751 Received 15 February 2018 Accepted 16 May 2018 Published 07 June 2018 Volume 9 - 2018 Edited by Kendal Hirschi, Baylor College of Medicine, United States Reviewed by Toshiro Shigaki, The University of Tokyo, Japan

In summary, Prx1 hyperoxidation allows cells to strike a fine balance between H 2 O 2 removal and limitation of mitochondrial glutathione oxidation, which is strongly predictive of cell death

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Persistent bleeding, sharp shooting pain suggesting nerve contact, or a hard lump that does not resolve should also prompt professional evaluation

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