liposomal glutathione side effects safety long term 15 Benefits: How to Improve Your Mind & Body Vitamin C and glutathione supplementation:

Microsomal system: An extremely important function of the microsomal cytochrome P450 monooxygenase system found associated with the membrane of the smooth endoplasmic reticulum (particularly in the liver) is the detoxification of foreign compounds (xenobiotics)

146 PappL

Newly formed Dglucuronides exhibit increased watersolubility and are easily eliminated from the body in urine or bile

Arch Biochem Biophys 373:302305 Pannirselvam M, Verma S, Anderson TJ, Triggle CR (2002) Cellular basis of endothelial dysfunction in small mesenteric arteries from spontaneously diabetic (db/db /) mice: role of decreased tetrahydrobiopterin bioavailability

The nuclear glutathione pool is more resistant to depletion by BSO than the cytosolic as it was demonstrated in 3T3 fibroblasts and other human cell lines 87,88 , hence we cannot exclude the possibility that AITC -which presumably acts differently from BSO- is able to deplete efficiently the nuclear pool