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Endocrine, 14(1), 110.

[6] [18] Proposed mechanisms include affecting GABA levels, blocking voltage-gated sodium channels, inhibiting histone deacetylases, and increasing LEF1

Side Effects and Safety Side effects Across preclinical studies and the small human trials published to date (~28 subjects across pilot studies), the reported adverse events stay limited: Mild injection-site irritation (rare) No systemic toxicity at therapeutic doses in published reports Oral administration: mild GI upset in sensitive individuals No immunosuppression, hormonal disruption, or metabolic side effects have been observed

NICE guideline [NG145]

Heavy periods with clots On top of your periods starting at random times, they can also be much heavier than they used to be