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Changes in alcohol consumption TLFB

Stimulate the production of melanin in hair, regulate the energy metabolism of hair follicle cells, eliminate free radicals on the skin, and inhibit the activity of 5-alpha-reductase

Dysregulation of these mechanisms compromises autoregulation, potentially transforming protective therapy into secondary ischemic insult

Smoking significantly exacerbates this risk, with recent evidence showing that cigarette smoking is associated with a 22% increased risk of CVD events in MASLD patients compared to non-smokers (aHR 1.22, 95% CI 1.151.30) [71]

Mechanism of Action IGF-1 LR3 binds to cell receptors in the muscle cells and activates cell communication, which then improves the growth rate of muscles