Another classic example is AMB, a potent antifungal drug that, when administered intravenously, can cause severe adverse effects, including kidney, liver, and cardiovascular damage, as well as anemia and electrolyte imbalances (Jarvis et al., 2022)
Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression
Rarer ones include gallbladder problems, pancreatitis, and gastroparesis, a chronic stomach condition that can cause serious pain, vomiting, and malnutrition
It is also the pathway that drugs like semaglutide act on, which is why every microbiome brand on earth now wants to talk about it, and why it is worth being careful here
Drug combinations often enhance therapeutic effect or cut needed dose, and similar strategies might reduce side effects in reproductive treatments