does semaglutide give energy Fatigue: Why It Happens & How to Fight It Semaglutide Fatigue: Causes, Effects, and

STRIDE (NCT04560998): Effect of semaglutide on functional capacity (change in maximum walking distance and pain free walking distance on tread mill, vascular quality) is being examined on 800 participants with peripheral arterial disorder

| Take home message According to data from two randomised controlled trials (STEP 1 and SUSTAIN 8), up to 40% of the weight lost on semaglutide (Wegovy/Ozempic) may be from lean mass

Users tend to be younger and more concentrated in the United States

Understanding these common reactions helps patients distinguish between expected, manageable symptoms and those requiring medical attention

(Some doctors had been prescribing Wegovy off-label for this purpose