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The Latin term, substantia nigra, means black substance

2.3 Hypertension and endothelial dysfunction Hypertension, or chronically elevated blood pressure, results from a combination of increased vascular resistance (often due to arterial constriction or stiffness) and sometimes elevated cardiac output

Blechter B, Cardenas A, Shi J, Wong JYY, Hu W, Rahman ML, Breeze C, Downward GS, Portengen L, Zhang Y, et al

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