If the wheal doesnt go away, talk to your doctor
Preclinical studies have shown potential benefits in wound healing, muscle recovery, and neurocognitive support
In particular, elective procedures with high consequence complications, including TJA, warrant carefully designed observational cohorts with validated patient-reported outcomes, wound surveillance, and adverse event monitoring
There are some theoretical risks to consider: Uncontrolled tissue growth, including fibrotic scar tissue Nerve ingrowth, which can contribute to chronic pain in tendons Potential tumour stimulation, given its role in promoting blood vessel formation In short, we dont yet know how it behaves in the human body over time, or how it might interact with other medications or health conditions
At the same time, more recent reviews emphasise that preclinical data predominate, so interpretation of the results should take into account the experimental nature of the substance and the limited number of high-quality clinical data