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Patients with severe gastrointestinal motility disorders (such as gastroparesis), history of bowel obstruction, or significant abdominal surgical history should discuss their potential increased risk with their provider before starting weight loss injections

For example, glutathione is required for transporting mercury away from the cells and brain

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While this observational study cannot prove causation, it raises important questions about whether GLP-1s could become part of future strategies for substance use disorders, overdose prevention, and post-overdose care management