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Immunity (2014) 41(1):1420

Sequence diversity and haplotype structure in the human ABCB1 (MDR1, multidrug resistance transporter) gene

FIGURE 2 3 The activation mechanism of eryptosis in renal anemia In the uremic milieu of CKD, a constellation of factorsincluding uremic toxin accumulation, chronic inflammation, oxidative stress, and hypoxiaconverge to induce cellular damage signals that promote eryptosis, the programmed death of erythrocytes

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We herein review perturbations in purine and neurotransmitter metabolism observed in early SZ using a metabolomic approach