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The NF-B pathway functions as a central pro-survival and pro-inflammatory transcription factor that promotes tumor progression by suppressing tumor suppressors such as phosphatase and tensin homolog (PTEN), thereby indirectly enhancing PI3K/AKT signaling and supporting cancer cell viability

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The ratio of reduced GSH to oxidised glutathione (GSSG) is widely used in research as a reliable indicator of intracellular oxidative stress, making Glutathione a key reference compound in studies examining cellular redox state across a broad range of experimental models