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Depending on their subtype, TAMs can produce either pro-inflammatory cytokines (e.g., IL-1 and IL-6) or anti-inflammatory cytokines (e.g., IL-4 and IL-10), thereby modulating the cytokine profile and shifting the tumor microenvironment toward either tumor suppression or tumor promotion (91)

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What is more selenium significantly influences the activation, proliferation, and differentiation of T cells during the initiation of immune response (242)

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