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2.1 Genomic findings Genomic and bioinformatic analyses followed a standardized workflow including QiAamp DNA extraction, Illumina DNA Prep with Exome 2.5 Enrichment, and XLEAP-SBS sequencing at ~100 coverage

The peptide activates PI3K/Akt signaling that translocates GLUT4 glucose transporters independent of insulin, bypassing normal feedback loops

Cancer Res 80(8):16301643 Niu Y, Zhang J, Tong Y, Li J, Liu B (2019) Physcion 8- O --glucopyranoside induced ferroptosis via regulating miR-103a-3p/GLS2 axis in gastric cancer

The chronic consumption of a Western-style diet, which is rich in saturated fats, refined carbohydrates, and processed foods, directly promotes weight gain and establishes a state of meta-inflammation

Wengert LA, Backe SJ, Bourboulia D, Mollapour M, Woodford MR