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Symptoms and Warnings Signs to Look Out For If youre concerned that the use of GLP-1 medication has caused a serious health issue, here are the most common warning signs of the complications described above: Frequent nausea Excessive vomiting Acid reflux (GERD) Severe abdominal pain Bloating or swelling of the abdomen Loss of appetite Lack of bowel movements If you have experienced any of the listed symptoms, seek medical attention right away