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While the overall frequency of liver enzyme elevations across the over 1,400 participant safety database of danuglipron is in-line with approved agents in the class, a single asymptomatic participant in one of the dose-optimization studies experienced potential drug-induced liver injury which resolved after discontinuation of danuglipron

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[DOI] [PubMed] [Google Scholar] 42.Scheibye-Knudsen M., Mitchell S.J., Fang E.F., Iyama T., Ward T., Wang J., et al

Federal law allows states to exclude agents used for weight loss from their Medicaid formularies so covering GLP-1s for obesity is optional, not required