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When oxidative stress occurs, G6PD normal RBCs maintain GSH levels by enhancing PPP activity, whereas in G6PD-deficient cells the PPP remains at minimum capacity and GSH levels decrease [49]

The ICR mice were used to establish an AD model in vivo , while PC12 cells (treated with A25-35) were used to build an in vitro AD model

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Characteristics of patients suffering from ASCVD and obesity without diabetes mellitus 7,256 patients had ASCVD and obesity, but no diabetes mellitus, corresponding to 0.50% of all inpatients or 3.16% of all ASCVD patients

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