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In the pathway of tyrosine metabolism, most of the experimental metabolites identified come from the adrenaline and noradrenaline degradation subpathway

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Chemosphere 56 , 659666 (2004)

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The mechanism: KPV translocates into the cell nucleus and blocks the interaction between importin-alpha3 and the p65/RelA subunit of NF-kB, preventing p65 from reaching its transcriptional targets