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National Institute of Neurological Disorders and Stroke (NINDS) - Authoritative resource on traumatic brain injury, stroke, neurodegenerative diseases, and the neuroscience of brain repair mechanisms

Metals like iron and copper are considered significant contributors to oxidative stress

This can be especially interesting for patients who are comparing braces and Invisalign but may not be ideal candidates for clear aligners

A person cannot determine their oxidative status from fatigue, headaches, muscle discomfort, poor concentration, or slow exercise recovery alone

This initiative has enabled the longitudinal tracking of biomarker trajectories and the development of composite endpoints that are gaining acceptance among regulatory agencies for clinical trial evaluation [608]